Personalized TMS Therapy

For Clinics & Hospitals

Make every TMS session count.

B1Neuro provides fMRI-based neurotargeting that integrates with your existing TMS hardware. Improve response rates without changing your clinical workflow.

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What we offer

Higher response rates

Patients on personalized protocols respond at significantly higher rates than those on standard scalp-based TMS — a 2.5x improvement in our clinical trials.

No hardware changes

Our neurotargeting layer works with your existing TMS device and neuronavigation system. We don’t ask you to switch equipment or retrain your team.

Validated approach

Personalized TMS is supported by published clinical trials and is in active use at medical centres and TMS clinics internationally.

The technology

What is fMRI-guided neurotargeting?

Standard TMS uses a generalized scalp landmarks to estimate the target location for stimulation. However, the optimal targets for brain stimulation treatments lie in individualized locations.

fMRI-guided neurotargeting uses a patient’s own resting-state fMRI scan to identify their individualized stimulation target, based on the functional connectivity of brain networks. The result is a treatment coordinate tailored to the patient, rather than a population average.

How it works

  1. Imaging acquisition. The clinic acquires a structural MRI (T1) and a resting-state fMRI scan from the patient. We provide imaging parameters compatible with standard clinical scanners (Siemens, GE, Philips).
  2. Data transfer. Imaging data is analysed by B1Neuro’s software. We can adapt the mode of data transfer to something that suits your institution.
  3. Brain network estimation. Our algorithms process the fMRI data to identify individual-specific functional networks, and computes an appropriate TMS target.
  4. Report delivery. A targeting report is delivered , ready for input into your clinic’s preferred neuronavigation system.

What we deliver

Each personalized targeting report includes:

  • Patient-specific stimulation target coordinates and neuronavigation-compatible files
  • Visual report showing the target within the patient’s brain anatomy
  • Quality assurance documentation

Backed by evidence

The clinical evidence behind personalized TMS continues to grow. Peer-reviewed studies have shown that fMRI-based targeting — using a patient’s own brain anatomy and functional connectivity — leads to higher response rates than standard scalp-based protocols. Beyond efficacy, fMRI targeting expands what’s possible: tailored protocols, network-level interventions, and treatment approaches for conditions.

Peer-reviewed research

Explore the published research underpinning our approach, including key studies on personalized targeting and brain network mapping.

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Ongoing clinical trials

We support and conduct clinical trials evaluating personalized TMS for depression and other conditions. See current and upcoming studies.

View clinical trials →

Get in touch

Partnerships

Request a technical brief or partnership conversation.
Email: leonooi@b1neuro.com

Research

Discuss collaboration, methodology, or trial participation.
Email: rubykong@b1neuro.com